In vitro and in vivo evaluation of folate receptor-targeting amphiphilic copolymer-modified liposomes loaded with docetaxel

@inproceedings{Li2011InVA,
  title={In vitro and in vivo evaluation of folate receptor-targeting amphiphilic copolymer-modified liposomes loaded with docetaxel},
  author={Xiang Li and Xin Tian and Jing Zhang and Xu Zhao and Xiaohui Chen and Youhong Jiang and Dongkai Wang and Weisan Pan},
  booktitle={International journal of nanomedicine},
  year={2011}
}
BACKGROUND The purpose of this study was to develop folate-poly (PEG-cyanoacrylate-co-cholesteryl cyanoacrylate) (FA-PEG-PCHL)-modified freeze-dried liposomes for targeted chemotherapy using docetaxel as a model drug. METHODS FA-PEG-PCHL was synthesized and its cytotoxicity was evaluated by CCK-8 assay in L929. Docetaxel-loaded liposomes modified by FA… CONTINUE READING