In vitro and in vivo evaluation of carbamazepine-loaded enteric microparticles.

@article{Dong2007InVA,
  title={In vitro and in vivo evaluation of carbamazepine-loaded enteric microparticles.},
  author={Wang Ya Dong and Philippe Maincent and Roland A Bodmeier},
  journal={International journal of pharmaceutics},
  year={2007},
  volume={331 1},
  pages={84-92}
}
The objective of the study was to prepare and evaluate carbamazepine-loaded enteric microparticles produced by a novel coacervation method. An aqueous polymeric stabilizer solution was added to an organic carbamazepine/Eudragit L100-55 solution. Water, which is a non-solvent for the drug and the enteric polymer, caused phase separation and the formation of coacervate droplets. These droplets hardened into microparticles upon further addition of the aqueous phase. The microparticles were… CONTINUE READING

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