In vitro and in vivo enhanced generation of human A9 dopamine neurons from neural stem cells by Bcl-XL.

@article{Courtois2010InVA,
  title={In vitro and in vivo enhanced generation of human A9 dopamine neurons from neural stem cells by Bcl-XL.},
  author={Elise T Courtois and Claudia G Castillo and Emma Gonzalez Seiz and Milagros Ramos and Carlos Bueno and Isabel Liste and Alberto Mart{\'i}nez-Serrano},
  journal={The Journal of biological chemistry},
  year={2010},
  volume={285 13},
  pages={9881-97}
}
Human neural stem cells derived from the ventral mesencephalon (VM) are powerful research tools and candidates for cell therapies in Parkinson disease. Previous studies with VM dopaminergic neuron (DAn) precursors indicated poor growth potential and unstable phenotypical properties. Using the model cell line hVM1 (human ventral mesencephalic neural stem cell line 1; a new human fetal VM stem cell line), we have found that Bcl-X(L) enhances the generation of DAn from VM human neural stem cells… CONTINUE READING

From This Paper

Figures and tables from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 23 extracted citations

Development of stem cell-based therapies for Parkinson's disease.

The International journal of neuroscience • 2016
View 3 Excerpts

References

Publications referenced by this paper.

NUMBER 13 JOURNAL OF BIOLOGICAL CHEMISTRY 9897 at U niersity of K asas M eical C eter/ A R D ykes

R. Geeta, R. L. Ramnath, H. S. Rao, V. Chandra
Biochem. Biophys. Res • 2008
View 1 Excerpt

Similar Papers

Loading similar papers…