In vitro and in vivo effects of rifabutin alone or combined with atovaquone against Toxoplasma gondii.

@article{Romand1996InVA,
  title={In vitro and in vivo effects of rifabutin alone or combined with atovaquone against Toxoplasma gondii.},
  author={St{\'e}phane Romand and C Della Bruna and Robert Farinotti and Francis Derouin},
  journal={Antimicrobial agents and chemotherapy},
  year={1996},
  volume={40 9},
  pages={2015-20}
}
The efficacy of rifabutin (RIFA) alone or in combination with atovaquone (ATO) was examined in vitro and in a murine model of acute toxoplasmosis. In vitro studies were performed with MRC5 fibroblast tissue cultures, with quantification of Toxoplasma growth by enzyme-linked immunosorbent assay. For in vivo studies, mice were acutely infected with 10(4… CONTINUE READING