In vitro and in vivo culture effects on mRNA expression of genes involved in metabolism and apoptosis in bovine embryos.

@article{Knijn2005InVA,
  title={In vitro and in vivo culture effects on mRNA expression of genes involved in metabolism and apoptosis in bovine embryos.},
  author={Hiemke M. Knijn and Christine Wrenzycki and Peter J. M. Hendriksen and Peter L. A. M. Vos and Elly C Zeinstra and Gijsbert C van der Weijden and Heiner Niemann and Steph J Dieleman},
  journal={Reproduction, fertility, and development},
  year={2005},
  volume={17 8},
  pages={775-84}
}
Bovine blastocysts produced in vitro differ substantially from their in vivo-derived counterparts with regard to glucose metabolism, level of apoptosis and mRNA expression patterns. Maternal embryonic genomic transition is a critical period in which these changes could be induced. The goals of the present study were twofold: (1) to identify the critical period of culture during which the differences in expression of gene transcripts involved in glucose metabolism are induced; and (2) to… CONTINUE READING

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