In vitro and in vivo assessment of intraintestinal bacteriotherapy in chronic kidney disease.

@article{Ranganathan2006InVA,
  title={In vitro and in vivo assessment of intraintestinal bacteriotherapy in chronic kidney disease.},
  author={Natarajan Ranganathan and Beena G Patel and Pari Ranganathan and Joseph Marczely and Rahul Dheer and Bohdan Pechenyak and Stephen R. Dunn and Willy Verstraete and Karel Decroos and Raj Mehta and Eli A. Friedman},
  journal={ASAIO journal},
  year={2006},
  volume={52 1},
  pages={70-9}
}
Chronic kidney disease may progress to end-stage renal disease, which requires dialysis or kidney transplantation. No generally applicable therapies to slow progression of renal disease are available. Bacteriotherapy affords a promising approach to mitigate uremic intoxication by ingestion of live microbes able to catabolize uremic solutes in the gut. The present study evaluates the nonpathogenic soil-borne alkalophilic urease-positive bacterium Sporosarcina pasteurii (Sp) as a potential urea… CONTINUE READING