Corpus ID: 31897913

In vitro and in vivo antifungal activity of the combination methylpartricin-5-fluorocytosine.

@article{Strippoli1984InVA,
  title={In vitro and in vivo antifungal activity of the combination methylpartricin-5-fluorocytosine.},
  author={V. Strippoli and A. Torosantucci and N. Simonetti},
  journal={Chemioterapia : international journal of the Mediterranean Society of Chemotherapy},
  year={1984},
  volume={3 2},
  pages={
          119-25
        }
}
In vitro studies on the antifungal activity exerted by the combinations SPA-S-222 (a hydrosoluble derivative of the polyene antibiotic methylpartricin) and 5-fluorocytosine evidence a favourable interaction against the formation of germ-tube in Candida albicans; against Cryptococcus neoformans and 5FC induced-resistant strains of Candida albicans. In the experimental infections with Candida albicans and Cryptococcus neoformans a significantly favourable interaction was exerted by polyene-5FC… Expand