In vitro and in silico evaluation of NF-κB targeted costunolide action on estrogen receptor-negative breast cancer cells--a comparison with normal breast cells.

@article{Pitchai2014InVA,
  title={In vitro and in silico evaluation of NF-κB targeted costunolide action on estrogen receptor-negative breast cancer cells--a comparison with normal breast cells.},
  author={Daisy Pitchai and Anita Roy and Sakhila K Banu},
  journal={Phytotherapy research : PTR},
  year={2014},
  volume={28 10},
  pages={1499-505}
}
Costunolide, a sesquiterpene lactone is a plant-derived secondary metabolite found to be present in most of the pharmacologically active herbs, being the cause for their medicinal values. The present study aims to evaluate the cytotoxic effect of costunolide isolated from Costus speciosus rhizome extract on MDA-MB-231 cells and explore its targeted action… CONTINUE READING