In vitro and bactericidal activities of ABT-492, a novel fluoroquinolone, against Gram-positive and Gram-negative organisms.

@article{Almer2004InVA,
  title={In vitro and bactericidal activities of ABT-492, a novel fluoroquinolone, against Gram-positive and Gram-negative organisms.},
  author={Laurel S Almer and Jennifer B Hoffrage and Erika L Keller and Robert K. Flamm and Virginia D. Shortridge},
  journal={Antimicrobial agents and chemotherapy},
  year={2004},
  volume={48 7},
  pages={
          2771-7
        }
}
In vitro activities of ABT-492, ciprofloxacin, levofloxacin, trovafloxacin, moxifloxacin, gatifloxacin, and gemifloxacin were compared. ABT-492 was more potent against quinolone-susceptible and -resistant gram-positive organisms, had activity similar to that of ciprofloxacin against certain members of the family Enterobacteriaceae, and had comparable activity against quinolone-susceptible, nonfermentative, gram-negative organisms. Bactericidal activity of ABT-492 was also evaluated. 
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