In vitro analysis and mechanical properties of twin screw extruded single-layered and coextruded multilayered poly(caprolactone) scaffolds seeded with human fetal osteoblasts for bone tissue engineering.

@article{Ergun2011InVA,
  title={In vitro analysis and mechanical properties of twin screw extruded single-layered and coextruded multilayered poly(caprolactone) scaffolds seeded with human fetal osteoblasts for bone tissue engineering.},
  author={Asli Ergun and Xiaojun Yu and Antonio D C Valdevit and Arthur Ritter and Dilhan M. Kalyon},
  journal={Journal of biomedical materials research. Part A},
  year={2011},
  volume={99 3},
  pages={
          354-66
        }
}
In vitro culturing and mechanical properties of three types of three-dimensional poly(caprolactone) scaffolds with interconnecting open-foam networks are reported. The scaffolds targeted bone tissue regeneration and were fabricated using twin screw extrusion and coextrusion techniques, for continuous mixing/shaping and formation of single or multilayers with distinct and tailorable porosities and pore sizes. Human fetal preosteoblastic cells, hFOB, were cultured on the extruded and coextruded… CONTINUE READING
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