In vitro activity of the tribactam GV104326 against gram-positive, gram-negative, and anaerobic bacteria.

@article{Modugno1994InVA,
  title={In vitro activity of the tribactam GV104326 against gram-positive, gram-negative, and anaerobic bacteria.},
  author={Enza Di Modugno and I Erbetti and Lucio Ferrari and Gianluca Galassi and Stephen M. Hammond and Luigi Xerri},
  journal={Antimicrobial agents and chemotherapy},
  year={1994},
  volume={38 10},
  pages={2362-8}
}
GV104326 is the first member of a new class of antibiotics (tribactams) selected for development. It combines a particularly broad spectrum (including gram-negative and gram-positive aerobes and anaerobes) with high potency, resistance to beta-lactamases, and complete stability to dehydropeptidases. Comparative MICs were determined for GV104326 against 415… CONTINUE READING