In vitro activity of the new ketolide HMR3647 in comparison with those of macrolides and pristinamycins against Enterococcus spp.

@article{Torres1998InVA,
  title={In vitro activity of the new ketolide HMR3647 in comparison with those of macrolides and pristinamycins against Enterococcus spp.},
  author={Carmen Torres and Myriam Zarazaga and Carmen Tenorio and A Pizarro Portillo and Yolanda S{\'a}enz and Facundo Ruiz and Fernando Baquero},
  journal={Antimicrobial agents and chemotherapy},
  year={1998},
  volume={42 12},
  pages={3279-81}
}
Ninety-four erythromycin-susceptible and 107 erythromycin-resistant enterococcal strains (MIC of >/=512 microgram/ml) were inhibited by the ketolide HMR3647 at MICs of </=0.007 to 0.06 and 0.03 to 8 microgram/ml, respectively. Eighteen vanA-positive isolates and 29 high-level-penicillin-resistant isolates, all of them erythromycin resistant, were inhibited by HMR3647 at an MIC range of 0.015 to 4 microgram/ml. The new ketolide has excellent activity against Enterococcus species. 

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