In vitro activity of the essential oil of Cinnamomum zeylanicum and eugenol in peroxynitrite-induced oxidative processes.

@article{Chericoni2005InVA,
  title={In vitro activity of the essential oil of Cinnamomum zeylanicum and eugenol in peroxynitrite-induced oxidative processes.},
  author={Silvio Chericoni and Jos{\'e} Maria Prieto and Patrizia Iacopini and Pierluigi Cioni and Ivano Morelli},
  journal={Journal of agricultural and food chemistry},
  year={2005},
  volume={53 12},
  pages={4762-5}
}
The essential oil obtained from the bark of Cinnamomum zeylanicum Blume (Lauraceae) and three of its main components, eugenol, (E)-cinnamaldehyde, and linalool (representing 82.5% of the total composition), were tested in two in vitro models of peroxynitrite-induced nitration and lipid peroxidation. The essential oil and eugenol showed very powerful activities, decreasing 3-nitrotyrosine formation with IC50 values of 18.4 microg/mL and 46.7 microM, respectively (reference compound, ascorbic… CONTINUE READING