• Corpus ID: 15841339

In vitro activity of some antimicrobial agents against infact and disrupted biofilms of staphylococci in the indwelling vascular catheter patients.

@article{ElShekh2010InVA,
  title={In vitro activity of some antimicrobial agents against infact and disrupted biofilms of staphylococci in the indwelling vascular catheter patients.},
  author={N. A. El-Shekh and Abrar Mohammed Ayoub and HodaH El-Hendawy and Emad A. Abada and Salem Khalifa},
  journal={World applied sciences journal},
  year={2010},
  volume={10},
  pages={108-120}
}
2 Abstract: Biofilm-associated infections are becoming more common and occur largely because of the increase usage of indwelling medical devices (for example, the catheter). Bacterial biofilms, which are micro-colonies encased in extracellular polysaccharide material (slime) are the sources of many bacterial infections which is so difficult to respond to routine treatments, also, shed cells or disrupted parts of the biofilm may enter the circulation causing serious and very hard to treat… 

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References

SHOWING 1-10 OF 35 REFERENCES
In vitro activity of vancomycin, quinupristin/dalfopristin, and linezolid against intact and disrupted biofilms of staphylococci
TLDR
The difficulty of treating biofilm-associated infections may be attributed not only to the difficulty of eradicating the biofilm focus but also to the lack of susceptibility of cells disrupted from the biofilms to antimicrobial agents.
Effect of vancomycin hydrochloride on Staphylococcus epidermidis biofilm associated with silicone elastomer.
TLDR
Data indicate that the biofilm organisms associated with an indwelling peritoneal catheter may display a form of tolerance, thereby suggesting one possible mechanism behind relapsing peritonitis.
Culture-Independent Microbiological Analysis of Foley Urinary Catheter Biofilms
TLDR
A culture-independent bacterial survey of Foley urinary catheters obtained from patients following total prostatectomy indicates the presence of diverse polymicrobial assemblages that were most commonly observed in patients who did not receive systemic antibiotics.
Microbial inactivation properties of a new antimicrobial/antithrombotic catheter lock solution (citrate/methylene blue/parabens)
TLDR
The new multicomponent lock solution has strong antimicrobial properties against both planktonic and sessile microorganisms, and may have usefulness in preventing bacterial colonization of haemodialysis catheters and diminishing the incidence of catheter-related bacteraemia.
Effect of Electrical Current on the Activities of Antimicrobial Agents against Pseudomonas aeruginosa, Staphylococcus aureus, and Staphylococcus epidermidis Biofilms
TLDR
The results of these experiments indicate that the enhancement of the activity of antimicrobial agent against biofilm organisms by EC is not a generalizable phenomenon across microorganisms and antimicrobial agents.
Adherence of slime-producing strains of Staphylococcus epidermidis to smooth surfaces
TLDR
The results suggest that slime-mediated adherence may be a critical factor in the pathogenesis of S. epidermidis infections of medical devices.
Antibiotic susceptibility assay for Staphylococcus aureus in biofilms developed in vitro.
TLDR
Transmission electron microscopy revealed that cells at the inner biofilm layers tend to remain intact after antibiotic treatment and that TSB-grown biofilms favoured a uniformity of cell distribution and increased cell density in comparison with milk-grownBiofilm aged revealed a reduced matrix distribution and enhanced cell density were observed as the biofilm aged.
In Vitro Activities of Telavancin and Vancomycin against Biofilm-Producing Staphylococcus aureus, S. epidermidis, and Enterococcus faecalis Strains
TLDR
Telavancin may have a unique role in biofilm-associated infections and vancomycin did not demonstrate the same activity against Staphylococcus aureus and Enterococcus faecalis.
Method of evaluating effects of antibiotics on bacterial biofilm
TLDR
A simple method of studying the effect of antibiotics on bacteria in established biofilms is reported and a combination containing 400 micrograms of each antibiotic per ml decreased the viable counts to an undetectable level in 24 h.
...
1
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3
4
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