In vitro activity of solithromycin and its metabolites, CEM-214 and N-acetyl-CEM-101, against 100 clinical Ureaplasma spp. isolates compared with azithromycin.

Abstract

There is a strong association between vaginal and/or amniotic fluid Ureaplasma spp. colonisation and risk of preterm birth. The novel fluoroketolide antibiotic solithromycin (CEM-101) is active against Ureaplasma spp. in vitro. Evidence from ex vivo and in vivo models suggests that, unlike most macrolide antibiotics, solithromycin readily crosses the… (More)
DOI: 10.1016/j.ijantimicag.2015.04.015

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@article{Furfaro2015InVA, title={In vitro activity of solithromycin and its metabolites, CEM-214 and N-acetyl-CEM-101, against 100 clinical Ureaplasma spp. isolates compared with azithromycin.}, author={Lucy L. Furfaro and Owen B Spiller and Jeffrey A Keelan and Matthew S. Payne}, journal={International journal of antimicrobial agents}, year={2015}, volume={46 3}, pages={319-24} }