In vitro activity of a new cephalosporin ME-1206 compared with other agents.

  title={In vitro activity of a new cephalosporin ME-1206 compared with other agents.},
  author={N. X. Chin and Y. X. Zhang and Harold C. Neu},
  journal={Diagnostic microbiology and infectious disease},
  volume={14 5},
  • N. Chin, Y. Zhang, H. Neu
  • Published 1 September 1991
  • Medicine, Biology
  • Diagnostic microbiology and infectious disease
Comparative Activity of Cefditoren and Other Oral β-Lactams against Nonpneumococcal Streptococci
The activity demonstrated by cefditoren against nonpneumococcal streptococci, including β-lactam- and macrolide-resistant isolates, suggests that this agent holds promise as therapy for infections caused by all clinically significant species of streptitisci.
Activity of cefditoren against respiratory pathogens.
Multistep studies of cefditoren, co-amoxiclav and cefprozil did not select for resistant mutants after 50 subcultures, compared with cefuroxime and azithromycin, where resistant mutants were selected in two and nine strains, respectively.
Cefditoren Pivoxil
Cefditoren pivoxil dosage regimens were as effective as a 10-day course of either cefadroxil 500mg once daily or cefuroxime axetil 250mg twice daily in treating uncomplicated skin and skin structure infections, including those caused by S. aureus and S. pyogenes.
Cefditoren, a New Aminothiazolyl Cephalosporin
Cefditoren pivoxil, an oral third‐generation cephalosporin, was approved by the Food and Drug Administration in September 2001 and has potential for empiric management of most commonly encountered respiratory tract infections.


beta-Lactam antibiotics: structural relationships affecting in vitro activity and pharmacologic properties.
  • H. Neu
  • Biology, Chemistry
    Reviews of infectious diseases
  • 1986
The essential nucleus of beta-lactam antibiotics is the four-membered ring, which can exist fused to form bicyclic ring structures or with moieties alone affixed to the four atoms. Penicillins,