In vitro activity and mode of action of diastereomeric antimicrobial peptides against bacterial clinical isolates.

Abstract

OBJECTIVES Increasing resistance of pathogenic bacteria to antibiotics is a severe problem in health care and has intensified the search for novel drugs. Cationic antibacterial peptides are the most abundant antibiotics in nature and have been frequently proposed as new anti-infective agents. Here, a group of diastereomeric (containing d- and l-amino acids… (More)

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