In vitro activity against anaerobes of retapamulin, a new topical antibiotic for treatment of skin infections.

@article{Odou2007InVA,
  title={In vitro activity against anaerobes of retapamulin, a new topical antibiotic for treatment of skin infections.},
  author={M. F. Odou and Claudette Muller and Laurent E. Calvet and Luc J Dubreuil},
  journal={The Journal of antimicrobial chemotherapy},
  year={2007},
  volume={59 4},
  pages={646-51}
}
OBJECTIVES Retapamulin is the first agent of the pleuromutilin class formulated as a topical antibacterial for treating skin infections. The aim of this study was to determine the antimicrobial activity of retapamulin by determining the minimal inhibitory concentration (MIC) values of this new drug and comparators against a wide range of anaerobic bacteria of human origin. METHODS The in vitro activity of retapamulin and six comparators (amoxicillin, amoxicillin/clavulanic acid, ceftriaxone… CONTINUE READING
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