In vitro activities of three new dihydrofolate reductase inhibitors against clinical isolates of gram-positive bacteria.

Abstract

BAL0030543, BAL0030544, and BAL0030545 are dihydrophthalazine inhibitors with in vitro potency against gram-positive pathogens. The MIC(50)s for methicillin (meticillin)-sensitive Staphylococcus aureus, methicillin-resistant Staphylococcus aureus, hetero-vancomycin-resistant Staphylococcus aureus, and vancomycin-resistant Staphylococcus aureus (VISA) range… (More)
DOI: 10.1128/AAC.00845-09

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@article{Bowker2009InVA, title={In vitro activities of three new dihydrofolate reductase inhibitors against clinical isolates of gram-positive bacteria.}, author={Karen E. Bowker and Patrick Caspers and B{\'e}reng{\`e}re Gaucher and Alasdair P Macgowan}, journal={Antimicrobial agents and chemotherapy}, year={2009}, volume={53 11}, pages={4949-52} }