In vitro activities of terbinafine against Aspergillus species in comparison with those of itraconazole and amphotericin B.

Abstract

Compared with the in vitro activities of itraconazole (geometric mean MIC [GM], 0.56 microg/ml) and amphotericin B (GM, 0.66 microg/ml), the in vitro activity of terbinafine was inferior against Aspergillus fumigatus (GM, 19.03 microg/ml) (P < 0.05) and superior against A. flavus (GM, 0.10 microg/ml), A. terreus (GM, 0.16 microg/ml), and A. niger (GM, 0.19 microg/ml). Clinical correlation is required, as trailing endpoints are problematic.

02040'03'05'07'09'11'13'15'17
Citations per Year

118 Citations

Semantic Scholar estimates that this publication has 118 citations based on the available data.

See our FAQ for additional information.

Cite this paper

@article{Moore2001InVA, title={In vitro activities of terbinafine against Aspergillus species in comparison with those of itraconazole and amphotericin B.}, author={Caroline Moore and Chelsi Morgan Walls and David W. Denning}, journal={Antimicrobial agents and chemotherapy}, year={2001}, volume={45 6}, pages={1882-5} }