In vitro activities of membrane-active peptides against gram-positive and gram-negative aerobic bacteria.

Abstract

Four peptides, cecropin P1, magainin II, indolicidin, and ranalexin, were evaluated against 202 clinical isolates of gram-positive and gram-negative aerobic bacteria by a microbroth dilution method. The gram-negative isolates were more susceptible to cecropin P1. Ranalexin was the most active compound against the gram-positive strains. The bactericidal… (More)

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@article{Giacometti1998InVA, title={In vitro activities of membrane-active peptides against gram-positive and gram-negative aerobic bacteria.}, author={Andrea Giacometti and Oscar Cirioni and Gianfranco Greganti and M. Quarta and Georgina D. Scalise}, journal={Antimicrobial agents and chemotherapy}, year={1998}, volume={42 12}, pages={3320-4} }