In vitro activities of linezolid against important gram-positive bacterial pathogens including vancomycin-resistant enterococci.

@article{Noskin1999InVA,
  title={In vitro activities of linezolid against important gram-positive bacterial pathogens including vancomycin-resistant enterococci.},
  author={Gary Noskin and Farida S Siddiqui and Valentina Stosor and Donna M. Hacek and Lance R. Peterson},
  journal={Antimicrobial agents and chemotherapy},
  year={1999},
  volume={43 8},
  pages={2059-62}
}
The emergence of resistance in gram-positive bacteria has necessitated a search for new antimicrobial agents. Linezolid is an oxazolidinone, a new class of antibacterial agents with enhanced activity against pathogens. We compared the activity of linezolid to those of other antimicrobial agents against 3,945 clinical isolates. Linezolid demonstrated potent activity against all isolates tested. For all vancomycin-susceptible enterococci, staphylococci, and streptococci, the activity of linezolid… CONTINUE READING