In vitro acetylation of HMGB-1 and -2 proteins by CBP: the role of the acidic tail.

@article{Pasheva2004InVA,
  title={In vitro acetylation of HMGB-1 and -2 proteins by CBP: the role of the acidic tail.},
  author={Evdokia A. Pasheva and Mihail Sarov and Kiril Bidjekov and Iva Ugrinova and Bettina Sarg and Herbert Lindner and Iliya G. Pashev},
  journal={Biochemistry},
  year={2004},
  volume={43 10},
  pages={2935-40}
}
Histone acetyltransferases CBP, PCAF, and Tip60 have been tested for their ability to in vitro acetylate HMGB-1 and -2 proteins and their truncated forms lacking the C-terminal tail. It was found that these proteins were substrates for CBP only. Analyses of modified proteins by electrophoresis, amino acid sequencing, and mass spectrometry showed that full… CONTINUE READING