In vitro T-cell responses to beta-lactam drugs in immediate and nonimmediate allergic reactions.

@article{Luque2001InVT,
  title={In vitro T-cell responses to beta-lactam drugs in immediate and nonimmediate allergic reactions.},
  author={Isabel Luque and Laura Alvarado Leyva and M Jos{\'e} Torres and Marta Alves Rosal and Cristobalina Mayorga and J. Segura and Miguel Blanca and Carlos Miguel Salazar Ju{\'a}rez},
  journal={Allergy},
  year={2001},
  volume={56 7},
  pages={611-8}
}
BACKGROUND beta-Lactam drugs may induce both cellular and humoral allergic reactions, and there is evidence that T cells play an important role in the pathogenesis of these reactions. The aim of this work was to assess the sensitivity and specificity of the lymphocyte transformation test (LTT) as an in vitro diagnostic tool, in patients with either an immediate or a nonimmediate reaction to penicillin G and/or amoxicillin. METHODS Fifty patients with a well-documented history of allergic… CONTINUE READING

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