In vitro IL-1 beta and TNF-alpha release from THP-1 monocytes in response to metal ions.

@article{Wataha1996InVI,
  title={In vitro IL-1 beta and TNF-alpha release from THP-1 monocytes in response to metal ions.},
  author={John C Wataha and S Ratanasathien and Carl Thomas Hanks and Zhuying Sun},
  journal={Dental materials : official publication of the Academy of Dental Materials},
  year={1996},
  volume={12 6},
  pages={322-7}
}
OBJECTIVES Previous studies have shown that biomaterials can activate macrophages to produce cytokines and promote an inflammatory response. Although the toxicity of many metal ions has been extensively investigated, little is known about the ability of these ions to alter cytokine release from macrophages. Yet the release of these ions from biomaterials has been well documented. Previous studies indicated that alterations in cytokine release might be expected because metal ions alter protein… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-9 of 9 extracted citations

Effect of Nickel Chloride on Cell Proliferation

The open dentistry journal • 2012
View 2 Excerpts

Similar Papers

Loading similar papers…