In vitro Broad Antiviral Function against HBV , HSV , H 3 N 2 Replication by Baicalin and Oroxylin A-7-O-Β-D-Glucoside

@inproceedings{An2017InVB,
  title={In vitro Broad Antiviral Function against HBV , HSV , H 3 N 2 Replication by Baicalin and Oroxylin A-7-O-Β-D-Glucoside},
  author={Duopeng An and Zhongbin Guan and Xiang Wang and Shui Yu and Yunxin Zhu and Hai Huang and Xiaoyuan Yang and Jiyang Li},
  year={2017}
}
Flavonoids have been previously shown to possess anti-viral activities In vitro. Oroxylin A-7-O-β-D-glucoside (OAG), a flavonoids produced by microbial conversion, and its substrate baicalin, were assayed for antiviral function against hepatitis B virus (HBV), herpes simplex virus type 2 (HSV-2) and influenza A virus (H3N2). Incubation with 100 μg/ml OAG or baicalin for 9 days reduced human HBV-transfected liver cell line HepG2 2.2.15 secretion of Hepatitis B surface antigen (HBsAg) by 83.17… CONTINUE READING

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