In vitro Broad Antiviral Function against HBV, HSV, H3N2 Replication byBaicalin and Oroxylin A-7-O-ÃÂ-D-Glucoside

@article{An2017InVB,
  title={In vitro Broad Antiviral Function against HBV, HSV, H3N2 Replication byBaicalin and Oroxylin A-7-O-{\~A}{\^A}-D-Glucoside},
  author={D. An and J. Li and Z. Guan and X. Wang and S. Yu and Yunxin Zhu and H. Huang and Xiaoyuan Yang},
  journal={Virology & Mycology},
  year={2017},
  volume={6},
  pages={1-5}
}
Flavonoids have been previously shown to possess anti-viral activities In vitro. Oroxylin A-7-O-β-D-glucoside (OAG), a flavonoids produced by microbial conversion, and its substrate baicalin, were assayed for antiviral function against hepatitis B virus (HBV), herpes simplex virus type 2 (HSV-2) and influenza A virus (H3N2). Incubation with 100 μg/ml OAG or baicalin for 9 days reduced human HBV-transfected liver cell line HepG2 2.2.15 secretion of Hepatitis B surface antigen (HBsAg) by 83.17… Expand
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