In utero exposure to low-dose 2,3',4,4',5-pentachlorobiphenyl (PCB 118) impairs male fertility and alters neurobehavior in rat offspring.

@article{Kuriyama2004InUE,
  title={In utero exposure to low-dose 2,3',4,4',5-pentachlorobiphenyl (PCB 118) impairs male fertility and alters neurobehavior in rat offspring.},
  author={Sergio Noboru Kuriyama and Ibrahim Chahoud},
  journal={Toxicology},
  year={2004},
  volume={202 3},
  pages={185-97}
}
Neurobehavior (motor activity and developmental reflexes) and male reproductive parameters were evaluated in rat offspring after in utero exposure to a low dose of PCB 118 comparable to human exposure levels. Sprague-Dawley dams were treated on gestation day 6 by gavage with a single dose of 375 microg PCB 118/kg body weight or peanut oil (control). The dose was calculated to be approximately 100-fold higher than that found in human breast milk. Postnatal reflexes, motor activity and male… CONTINUE READING
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