In utero exposure of mice to diethylstilbestrol alters neonatal ovarian follicle growth and development.

@article{Wordinger1989InUE,
  title={In utero exposure of mice to diethylstilbestrol alters neonatal ovarian follicle growth and development.},
  author={Robert J. Wordinger and J Derrenbacker},
  journal={Acta anatomica},
  year={1989},
  volume={134 4},
  pages={312-8}
}
The prenatal exposure of mice to diethylstilbestrol (DES, 10 micrograms/kg on day 15 of gestation) caused both quantitative and structural alterations in ovarian follicles within the neonatal ovary. At birth, control ovaries consisted of small type 1 and 2 ovarian follicles located in the ovarian cortex. By postnatal day 7, ovarian follicle development had advanced to the type 4 stage with larger follicles located within the ovarian medulla. In DES-exposed animals, ovarian follicle maturation… CONTINUE READING

From This Paper

Topics from this paper.