In utero ethanol exposure decreased the density of serotonin neurons. Maternal ipsapirone treatment exerted a protective effect.

@article{Tajuddin1999InUE,
  title={In utero ethanol exposure decreased the density of serotonin neurons. Maternal ipsapirone treatment exerted a protective effect.},
  author={Nuzhath F Tajuddin and Mary J Druse},
  journal={Brain research. Developmental brain research},
  year={1999},
  volume={117 1},
  pages={91-7}
}
Prior studies from this laboratory showed that in utero ethanol exposure severely retards the development of the serotonin (5-HT) system; we demonstrated a reduced concentration of 5-HT and 5-HT reuptake sites and alterations in the concentration of 5-HT(1A) receptors in ethanol-exposed offspring. These investigations also found that maternal treatment with a 5-HT(1A) agonist, buspirone, prevented most of the ethanol-associated damage to the developing 5-HT system. In the present investigation… CONTINUE READING

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