In-tube moleculary imprinted polymer solid-phase microextraction for the selective determination of propranolol.

@article{Mullett2001IntubeMI,
  title={In-tube moleculary imprinted polymer solid-phase microextraction for the selective determination of propranolol.},
  author={Wayne M. Mullett and Peter M Martin and Janusz Pawliszyn},
  journal={Analytical chemistry},
  year={2001},
  volume={73 11},
  pages={2383-9}
}
A molecularly imprinted polymer (MIP) material was synthesized for use as an in-tube solid-phase microextraction (SPME) adsorbent. The inherent selectivity and chemical and physical robustness of the MIP material was demonstrated as an effective stationary-phase material for in-tube SPME. An automated and on-line MIP SPME extraction method was developed for propranolol determination in biological fluids. This simplified the sample preparation process and the chromatographic separation of… CONTINUE READING

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