In the eye of the storm: T cell behavior in the inflammatory microenvironment.

  title={In the eye of the storm: T cell behavior in the inflammatory microenvironment.},
  author={R. Haas and Federica M. Marelli-Berg and Claudio Mauro},
  journal={American journal of clinical and experimental immunology},
  volume={2 2},
Coordinated unfolding of innate and adaptive immunity is key to the development of protective immune responses. This functional integration occurs within the inflamed tissue, a microenvironment enriched with factors released by innate and subsequently adaptive immune cells and the injured tissue itself. T lymphocytes are key players in the ensuing adaptive immunity and their proper function is instrumental to a successful outcome of immune protection. The site of inflammation is a "harsh… CONTINUE READING


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