In situ structural characterization of phosphatidylcholines in brain tissue using MALDI-MS/MS.

@article{Jackson2005InSS,
  title={In situ structural characterization of phosphatidylcholines in brain tissue using MALDI-MS/MS.},
  author={Shelley N Jackson and H J Wang and Amina S Woods},
  journal={Journal of the American Society for Mass Spectrometry},
  year={2005},
  volume={16 12},
  pages={2052-6}
}
Phosphatidylcholine (PC) is one of the most abundant classes of phospholipids and is a major component of membranes in biological systems. Recently, PCs have been detected by direct tissue analysis using MALDI-TOFMS. However, these studies did not allow for the structural characterization of PCs in tissue. In the current study, an in situ method for detection and structural analysis of PC species in brain tissue was developed using a MALDI-TOF/TOF mass spectrometer. Initial profiling of lipids… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 39 extracted citations

Similar Papers

Loading similar papers…