In situ hybridization with biotinylated DNA probes: a rapid diagnostic test for adenovirus upper respiratory infections.

Abstract

Adenovirus DNA was detected in cells from nasopharyngeal secretions of children with acute respiratory infections by in situ hybridization with biotinylated probes. The technique was easy to perform, giving rapid results which were well correlated with those of immunofluorescence assays of the same samples. Adenoviruses of subgroups B, C and E were detected… (More)

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