In situ human telomerase reverse transcriptase expression pattern in normal and neoplastic ovarian tissues.

@article{Baykal2004InSH,
  title={In situ human telomerase reverse transcriptase expression pattern in normal and neoplastic ovarian tissues.},
  author={Atac Baykal and Jennifer A. Thompson and X{\`i}ao-chun Xu and William C. Hahn and Michael T. Deavers and Anais Malpica and David M. Gershenson and Elvio Gilberto da Silva and Jinsong Liu},
  journal={Oncology reports},
  year={2004},
  volume={11 2},
  pages={297-302}
}
Telomerase is a ribonuclear protein reverse transcriptase that maintains telomere length in eukaryotic cells. Activation of telomerase has been implicated in human cellular immortalization and carcinogenesis. Telomerase activity in ovarian neoplasm has been studied using polymerase chain reaction (PCR)-based methods and shown to be correlated with malignancy. However, we believe those results must be interpreted with caution because such studies used a heterogeneous mix of cells, including… CONTINUE READING

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