In situ gold nanoparticle growth on polydopamine-coated 3D-printed scaffolds improves osteogenic differentiation for bone tissue engineering applications: in vitro and in vivo studies.

@article{Lee2018InSG,
  title={In situ gold nanoparticle growth on polydopamine-coated 3D-printed scaffolds improves osteogenic differentiation for bone tissue engineering applications: in vitro and in vivo studies.},
  author={Sang Jin Lee and Hyo-Jung Lee and Sung-Yeol Kim and Ji Min Seok and Jun Hee Lee and Wan Doo Kim and Il Keun Kwon and Shin-Young Park and Su A. Park},
  journal={Nanoscale},
  year={2018},
  volume={10 33},
  pages={
          15447-15453
        }
}
In this study, we designed scaffolds coated with gold nanoparticles (GNPs) grown on a polydopamine (PDA) coating of a three-dimensional (3D) printed polycaprolactone (PCL) scaffold. Our results demonstrated that the scaffolds developed here may represent an innovative paradigm in bone tissue engineering by inducing osteogenesis as a means of remodeling and healing bone defects. 
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