In situ gene expression of growth hormone (GH) receptor and GH binding protein in adult male rat tissues.

@article{Mertani1995InSG,
  title={In situ gene expression of growth hormone (GH) receptor and GH binding protein in adult male rat tissues.},
  author={Hichem C. Mertani and G{\'e}rard Morel},
  journal={Molecular and cellular endocrinology},
  year={1995},
  volume={109 1},
  pages={47-61}
}
Pituitary growth hormone (GH) acts as a growth promoter in a wide range of tissues after binding to its specific GH receptor (GHR) or to a cytosolic circulating GH binding protein (GHBP). To further characterize GH target cells in the rat, in situ hybridization was used to investigate the tissue and cell distribution of mRNAs encoding GHR and GHBP, and their hepatic developmental expression was examined. Cryostat sections of adult male rat tissue were hybridized with [35S]dATP-labeled… CONTINUE READING
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