In situ forming microparticle implants for delivery of sex steroids in fish: Modulation of the immune response of gilthead seabream by testosterone.

@article{CastilloBriceo2013InSF,
  title={In situ forming microparticle implants for delivery of sex steroids in fish: Modulation of the immune response of gilthead seabream by testosterone.},
  author={Patricia Castillo-Brice{\~n}o and S Aguila-Mart{\'i}nez and Sergio Liarte and A Garc{\'i}a Alc{\'a}zar and Jose Jaime Meseguer and Victoriano Mulero and Alfonsa Garc{\'i}a-Ayala},
  journal={Steroids},
  year={2013},
  volume={78 1},
  pages={26-33}
}
Current knowledge on the sensitivity of marine fish to androgenic environmental chemicals is limited, despite the growing interest in the effects of endocrine disrupting chemicals. To study in vivo the effects of testosterone (T) on the fish immune response, we used a microencapsulation implant technique, the in situ forming microparticle system, containing 1 mg T/kg body weight (T-ISM), in adult specimens of gilthead seabream (Sparus aurata L.), a species of great economic interest. We… CONTINUE READING

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