In situ expression of interleukin-10 in noninflamed human gut and in inflammatory bowel disease.

@article{Autschbach1998InSE,
  title={In situ expression of interleukin-10 in noninflamed human gut and in inflammatory bowel disease.},
  author={Frank Autschbach and Jutta Braunstein and Burkhard H Helmke and Ivan Zuna and Guido Schuermann and Zofia I. Niemir and Reinhard Wallich and Herwart F. Otto and Stefan C. Meuer},
  journal={The American journal of pathology},
  year={1998},
  volume={153 1},
  pages={121-30}
}
A dysregulated secretion of contra-inflammatory cytokines such as interleukin-10 (IL-10) could play a role in the pathogenesis of inflammatory bowel disease (IBD). We have investigated the expression of IL-10 in gut tissues from patients with Crohn's disease (CD), ulcerative colitis (UC) and controls by mRNA in situ hybridization and immunohistochemistry. Intestinal epithelial cells were found to express IL-10 mRNA and IL-10 protein in all of the tissues investigated without any major… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 48 extracted citations

Similar Papers

Loading similar papers…