In situ demonstration of dendritic cell migration from rat intestine to mesenteric lymph nodes: relationships to maturation and role of chemokines.

@article{Kobayashi2004InSD,
  title={In situ demonstration of dendritic cell migration from rat intestine to mesenteric lymph nodes: relationships to maturation and role of chemokines.},
  author={Hisashi Kobayashi and Soichiro Miura and Hiroshi Nagata and Yoshikazu Tsuzuki and Ryota Hokari and Takashi Ogino and Chikako Esther Watanabe and Toshifumi Azuma and Hiromasa Ishii},
  journal={Journal of leukocyte biology},
  year={2004},
  volume={75 3},
  pages={
          434-42
        }
}
Dendritic cells (DCs) are continuously transported from the intestine to mesenteric lymph nodes (MLNs). The objective of this study was to determine the migration kinetics of DCs via intestinal lymph and to investigate regulatory factors affecting their migration in vivo. DCs were obtained from spleen or thoracic duct lymph of mesenteric lymphadenectomized rats. The DCs were fluorescently labeled and injected into the subserosa of the small intestine near the cecum, and their migration patterns… CONTINUE READING

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