In situ collagen gelation: A new method for constructing large tissue in rotary culture vessels

Abstract

In situ collagen gelation is a method that combines a static three-dimensional culture technique with rotating bioreactors. This method was designed for large dense tissue engineering ex vivo. To challenge the current limitations on size, we combined the static collagen gel embedding method with high-aspect ratio rotating bioreactors. Rat calvarial cells in… (More)
DOI: 10.1290/1543-706X(2003)039<0368:ISCGAN>2.0.CO;2

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