In situ GABAergic modulation of synchronous gonadotropin releasing hormone-1 neuronal activity.

@article{Moore2002InSG,
  title={In situ GABAergic modulation of synchronous gonadotropin releasing hormone-1 neuronal activity.},
  author={Joseph Patrick Moore and Eric K Shang and Susan Wray},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={2002},
  volume={22 20},
  pages={8932-41}
}
Evidence indicates that gonadotropin releasing hormone-1 [GnRH-1, also known as luteinizing hormone releasing hormone (LHRH)] neurons can exhibit synchronized neuroendocrine secretory activity before entrance into the CNS. In this study, we used calcium imaging to evaluate patterns of activity in individual, embryonic, GnRH-1 neurons as well as population dynamics of GnRH-1 neurons in mouse nasal explants maintained for 1 versus 3 weeks. Independent of age, GnRH-1 neurons displayed significant… CONTINUE READING

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