In silico studies of urease inhibitors to explore ligand-enzyme interactions.

Abstract

In continuation of our previous study on the urease inhibition by a number of chalcones, 2,3-dihydro-1,5-benzothiazepines and 2,3,4,5-tetrahydro-1,5-benzothiazepines, FlexX docking has been exploited to get a deeper insight into the mechanism of their inhibitory action. A comparison of the IC(50) values of the active compounds reveals that, of the three… (More)
DOI: 10.1080/14756360801945598

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Cite this paper

@article{Ansari2009InSS, title={In silico studies of urease inhibitors to explore ligand-enzyme interactions.}, author={Farzana Latif Ansari and Abdul Wadood and Ahsan Ullah and Fatima Iftikhar and Zaheer ul-Haq}, journal={Journal of enzyme inhibition and medicinal chemistry}, year={2009}, volume={24 1}, pages={151-6} }