In silico investigation of action mechanism of four novel angiotensin-I converting enzyme inhibitory peptides modified with Trp

@inproceedings{Xie2015InSI,
  title={In silico investigation of action mechanism of four novel angiotensin-I converting enzyme inhibitory peptides modified with Trp},
  author={Cheng-liang Xie and Se Young Choung and Guang-ping Cao and Keun Woo Lee and Yeung Joon Choi},
  year={2015}
}
To potentiate activities of angiotensin-I converting enzyme (ACE) inhibitory peptides VK, YA, KY and TAY from oyster hydrolysate, four novel tripeptides VKW, YAW, KYW and TAW were designed by modification with Trp at the C-terminus. The tripeptides were synthesized, and their 50% ACE inhibitory concentrations (IC50) were measured to be 0.020, 0.49, 0.43 and… CONTINUE READING