In silico identification of lysocin biosynthetic gene cluster from Lysobacter sp. RH2180-5

@article{Panthee2017InSI,
  title={In silico identification of lysocin biosynthetic gene cluster from Lysobacter sp. RH2180-5},
  author={Suresh Panthee and Hiroshi Hamamoto and Yutaka Suzuki and Kazuhisa Sekimizu},
  journal={The Journal of Antibiotics},
  year={2017},
  volume={70},
  pages={204-207}
}
In silico identification of lysocin biosynthetic gene cluster from Lysobacter sp. RH2180-5 
Identification of the biosynthetic gene cluster for the anti-MRSA lysocins through gene cluster activation using strong promoters of housekeeping genes and production of new analogs in Lysobacter sp. 3655.
TLDR
With readily detectable lysocins production in the engineered strains, it is shown that lysOCin production was abolished in the gene deletion mutant and then restored in the complementary strain, even when grown in conditions that did not support the wild type for lysoin production. Expand
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The Role of Amino Acid Substitution in HepT Toward Menaquinone Isoprenoid Chain Length Definition and Lysocin E Sensitivity in Staphylococcus aureus
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TLDR
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Antibiotics from Gram-negative bacteria: a comprehensive overview and selected biosynthetic highlights.
TLDR
A comprehensive list of natural products with antimicrobial activity from Gram-negative bacteria, including information on their biosynthetic origin(s) and molecular target(s), where known. Expand
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TLDR
The structural diversity, activity and biosynthesis of lysobacterial antibiotics are summarized and the importance of Lysobacter species for antibiotic production is highlighted. Expand
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TLDR
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A Novel Spiro-Heterocyclic Compound Identified by the Silkworm Infection Model Inhibits Transcription in Staphylococcus aureus
TLDR
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