In silico identification of epitopes in Mycobacterium avium subsp. paratuberculosis proteins that were upregulated under stress conditions.

@article{Gurung2012InSI,
  title={In silico identification of epitopes in Mycobacterium avium subsp. paratuberculosis proteins that were upregulated under stress conditions.},
  author={Ratna B Gurung and Auriol C. Purdie and Douglas J. Begg and Richard J Whittington},
  journal={Clinical and vaccine immunology : CVI},
  year={2012},
  volume={19 6},
  pages={
          855-64
        }
}
Johne's disease in ruminants is caused by Mycobacterium avium subsp. paratuberculosis. Diagnosis of M. avium subsp. paratuberculosis infection is difficult, especially in the early stages. To date, ideal antigen candidates are not available for efficient immunization or immunodiagnosis. This study reports the in silico selection and subsequent analysis of epitopes of M. avium subsp. paratuberculosis proteins that were found to be upregulated under stress conditions as a means to identify… CONTINUE READING
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