In-silico designing of acyclic nucleoside phosphonates and their anti-HIV potential


Method The object of our study is to develop newer nucleoside phosphonate analogs bearing unsaturation and modifications in heterogenous bases and prediction of their antiHIV potential. Designing is done keeping the Lipinski’s Rule of Five in focus. The diphosphates of compounds have been docked into the active site of wild type HIVRT (PDB: ID 2B6A). The… (More)


Figures and Tables

Sorry, we couldn't extract any figures or tables for this paper.