In silico characterization of the family of PARP-like poly(ADP-ribosyl)transferases (pARTs)

@article{Otto2005InSC,
  title={In silico characterization of the family of PARP-like poly(ADP-ribosyl)transferases (pARTs)},
  author={Helge Otto and Pedro A. Reche and Fernando M. Baz{\'a}n and Katharina Dittmar and Friedrich Haag and Friedrich Koch-Nolte},
  journal={BMC Genomics},
  year={2005},
  volume={6},
  pages={139 - 139}
}
BackgroundADP-ribosylation is an enzyme-catalyzed posttranslational protein modification in which mono(ADP-ribosyl)transferases (mARTs) and poly(ADP-ribosyl)transferases (pARTs) transfer the ADP-ribose moiety from NAD onto specific amino acid side chains and/or ADP-ribose units on target proteins.ResultsUsing a combination of database search tools we identified the genes encoding recognizable pART domains in the public genome databases. In humans, the pART family encompasses 17 members. For 16… CONTINUE READING
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