In silico approach towards identification of potential inhibitors of Helicobacter pylori DapE.

Abstract

Helicobacter pylori is a gastric mucosal pathogen and is associated with diseases like peptic ulcer and gastric cancer. To combat H. pylori infection, there is an urgent need for new class of antibiotics due to the emergence of drug-resistant strains. Enzymes involved in bacterial lysine biosynthetic pathways may be potential targets for antibacterial drug… (More)
DOI: 10.1080/07391102.2014.954272

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