In silico and in vivo evaluation of bacteriophage phiEF24C, a candidate for treatment of Enterococcus faecalis infections.

@article{Uchiyama2008InSA,
  title={In silico and in vivo evaluation of bacteriophage phiEF24C, a candidate for treatment of Enterococcus faecalis infections.},
  author={Jumpei Uchiyama and Mohammad Rashel and Iyo Takemura and Hiroshi Wakiguchi and Shigenobu Matsuzaki},
  journal={Applied and environmental microbiology},
  year={2008},
  volume={74 13},
  pages={4149-63}
}
Along with the increasing threat of nosocomial infections by vancomycin-resistant Enterococcus faecalis, bacteriophage (phage) therapy has been expected as an alternative therapy against infectious disease. Although genome information and proof of applicability are prerequisites for a modern therapeutic phage, E. faecalis phage has not been analyzed in terms of these aspects. Previously, we reported a novel virulent phage, phiEF24C, and its biology indicated its therapeutic potential against E… CONTINUE READING